TachoSil®–The gold standard in surgical excellence.

The ready-to-use
solution for hemostasis

TachoSil is a fibrin sealant patch coated with fibrinogen and thrombin that activates on contact with blood to deliver fast, effective control of bleeding. With proven efficacy across open and minimally invasive procedures, it combines mechanical strength with physiologic hemostasis. Developed from TachoComb and trusted since 2004.

Own the moment
of responsibility.

Minimally invasive. Maximum control. Reliable hemostasis in robotic surgery.

TachoSil seamlessly integrates into minimally invasive and open workflows, combining trusted performance with precision.

Full effect. No traces.
TachoSil supports controlled bleeding management with minimal intervention—and without the need for removal.
Combined active structure.
TachoSil is a ready-to-use combination of a
fibrin sealant patch coated with the human
coagulation factors fibrinogen and thrombin¹. This
combination supports rapid hemostasis by
activating the body’s own coagulation system.
The biological degradation 

of TachoSil.
After 4 weeks
The sealant matrix is fully integrated into the surrounding serosa. Dense connective tissue and 
new blood vessels form a stable layer over the 
patch.

After 12 weeks
The material is gradually replaced by granulation tissue. The sealant matrix is absorbed step by step 
— leaving no foreign material behind.
One solution. Multiple formats. For maximum surgical flexibility.

TachoSil comes in a double sterile package. The folding box contains the package leaflet and an aluminium composite foil container. Air and thus moisture are kept out by this heat-sealed aluminium foil. This ensures that fibrinogen and thrombin do not react with each other prematurely and the full adhesive strength remains until it is applied.

TachoSil Fibrin Sealant Patch
Ready-to-use for MIS and open surgical procedures.
Ideal for reliable hemostasis in a variety of specialties. Available sizes: 9.5 × 4.8 cm and 4.8 × 4.8 cm

Downloads

TachoSil Compendium
Case example: Application of closed cell collagen matrix after ascending aorta and aortic arch replacement
Case example: Use of TachoSil® after transcatheter aortic valve implantation (TAVI*) due to aortic valve stenosis
Case example: Hemostasis of liver resection surfaces in the case of hepatocellular carcinoma
Case example: Hemostasis following traumatic liver injury

View TachoSil in action.

Ready. Steady. Go.

Easy to use, with no need for mixing or preparation. TachoSil helps reduce complications, lowers intraoperative risks, and supports faster decision-making—so you can operate with more confidence and focus on what truly matters: your patient.

Application made easy.

1
Open aluminum blister
Open the peel-away film of the external packaging (aluminium blister) – can be opened in a non-sterile zone.
2
Open plastic blister
Open the packaging in a sterile zone with sterile gloves.
3
Grasp
Remove the patch from the sterile packaging with forceps.
4
Trim (Optional)
The patch can be trimmed to size, but it is important that it extends 1 – 2 cm beyond the wound margin.
5
Moisten (Optional)
If the wound is dry, it is recommended to moisten the TachoSil before application. If the wound is already wet, it can be applied dry.
6
Apply
The patch is applied with the yellow active side facing the treated area. If larger areas need to be treated with more than one patch, they should be overlapped like roof tiles.
7
Press in place
The patch must be pressed in place gently for up to 3 minutes, ideally with a moist compress.
8
Remove the compress
Remove the moist compress carefully, using forceps if necessary.

Ready for
the future.

Precision in every layer.
Safety in every step.

Innovation made in Austria since 1992: TachoSil has been manufactured in Linz since 2004, building on the legacy of TachoComb. Produced in class C cleanrooms, it meets the highest pharmaceutical quality standards.

Note: The information in this manufacturing video is not country specific and may vary from the approved product information in the country where you are located. Not all sizes and formulations of TachoSil are available in all markets.

A trusted name worldwide.

Used in operating rooms around the world, TachoSil stands for reliability, safety, and consistent surgical performance—wherever it’s needed.

References

1: Summary of Product Characteristics TachoSil.


COR-BS26-0001-R0
TACHOSIL SmPC
List Item Icon
Links to regional SMPC:


Abbreviated SmPC:

TachoSil® Fibrin Sealant Patch

Presentation: TachoSil is a topical fibrin sealant patch consisting of human fibrinogen and human thrombin coated onto an equine collagen sponge. The active side of the patch is yellow and the non-active side is off-white in color.

Indication and Important Safety Information
Indications: TachoSil is a fibrin sealant patch indicated for use with manual compression in adult and pediatric patients as an adjunct to hemostasis in cardiovascular and hepatic surgery when control of bleeding by standard surgical techniques (such as suture, ligature or cautery) is ineffective or impractical.
Limitations for Use: TachoSil cannot safely or effectively be used in place of sutures or other form of mechanical ligation for the treatment of major arterial or venous bleeding. • Not for use in children under one month of age.
Dosage & Administration: For topical use on cardiovascular or hepatic tissue only • Determine the number of patches to be applied by the size of the bleeding area. • Apply the yellow, active side of the patch to the bleeding area. • When applying TachoSil, do not exceed the maximum number of patches. Refer to the Full Prescribing Information for details on administration and maximum number of patches.
Contraindications: Do not apply TachoSil intravascularly. Intravascular application of TachoSil may result in life threatening thromboembolic events. • Do not use TachoSil in individuals known to have anaphylactic or severe systemic reaction to human blood products or horse proteins.
Warnings & Precautions:
Thrombosis. Thrombosis can occur if TachoSil is applied intravascularly. Ensure that TachoSil is applied to the surface of cardiac, vascular, or hepatic tissue only.
Hypersensitivity Reactions. Hypersensitivity or allergic/anaphylactoid reactions may occur in patients receiving TachoSil for the first time or may increase with repetitive applications.
Infection. Avoid application to contaminated or infected areas of the body, or in the presence of active infection.
Adhesions. TachoSil contains collagen, which may adhere to bleeding surfaces. May carry a risk of gastrointestinal obstruction in abdominal surgery due to tissue adhesions. To prevent the development of tissue adhesions at undesired sites, ensure tissue areas outside the desired application area are adequately cleansed before administration of TachoSil.
Compression. Avoid packing in cavities or closed spaces because this may cause compression of underlying tissue.
Non-Adherence or Dislodged Material. Use only the minimum number of TachoSil patches necessary to achieve hemostasis. Do not pack. Remove unattached pieces of TachoSil.
Transmissible Infectious Agents. May carry a risk of transmitting infectious agents, such as viruses, and theoretically, the variant Creutzfeldt-Jakob disease (vCJD) agent and the Creutzfeldt-Jakob disease (CJD) agents.
Use in specific populations: Pediatric Use: Use of TachoSil in children under the age of one month may be unsafe or ineffective due to small size and limited ability to apply the patch as recommended.
Adverse Reactions: The adverse reactions reported in more than 1% of patients during clinical trials were anemia, nausea and vomiting, fever, abdominal pain, increased white blood cell count, ascites, itching, atrial fibrillation, pleural effusion, gastrointestinal hemorrhage, wound infection, hypophosphatemia, urinary tract infection, and post-procedural bile leakage in hepatic surgery. Refer to the Full prescribing Information for details on, contraindications, warnings, precautions, and adverse reactions.
Marketing Authorisation Holder: Corza Medical GmbH, Speditionstrasse 21, 40221 Düsseldorf, Germany. US License no. 2294.Revision date: 08/2025

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